NK cells, the natural enemy of cancer cells Imagine that your body is a castle, and NK cells (natural killer cells) are the guards patrolling day and night, ready to deal with the lurking enemy - cancer cells. However, due to the disease and treatment process, more than 95% of cancer patients have a serious lack of NK cells and activity in their bodies, which provides loopholes for cancer cells to relapse. Through NK cell re-infusion therapy, these "guards" can return to their posts and escort the recovery of tumors after surgery.

PART 01 

The power of NK cells: a secret weapon to fight cancer cells NK cells are the first line of defense of the immune system. They do not need to identify the enemy in advance, but only need to sense the presence of abnormal cells to launch an attack decisively. They break the "protective wall" of cancer cells by releasing perforins and granzymes, triggering cell apoptosis from the inside. Unfortunately, the immune system of cancer patients is often exhausted, and the number and activity of NK cells drop significantly. This "defense line loss" not only makes it easy for cancer cells to spread, but also increases the risk of postoperative recurrence.

PART 02 

Clinical data: Association between postoperative recurrence and NK cell deficiency

Multiple clinical studies have found that NK cell activity is closely related to the prognosis of cancer patients.

In various cancer types such as liver cancer and non-Hodgkin's lymphoma, there is a high correlation between the reduced activity of NK cells in patients and the significantly increased recurrence rate.

Studies have also shown that the function of NK cells in cancer patients is further weakened after receiving radiotherapy and chemotherapy, and there is an urgent need to restore their immune activity through intervention. 

PART 03 

Reinfusion of NK cells: an effective weapon for postoperative recurrence prevention

By reinfusing autologous or allogeneic NK cells, the patient's immune system is enhanced.

These cells are amplified in vitro and then injected into the body, just like replenishing ammunition for soldiers on the battlefield, allowing them to quickly restore their combat effectiveness.

Studies have shown that patients who receive NK cell reinfusion have a significantly reduced risk of recurrence and a prolonged overall survival.

Case sharing: The efficacy of NK cell reinfusion

A study of patients with non-small cell lung cancer showed that the tumor recurrence rate was reduced by more than 30% after patients received NK cell reinfusion treatment after surgery.

Another study pointed out that in patients with liver cancer, the therapy of reinfusing NK cells significantly improved the patients' progression-free survival (PFS), showing the potential of NK cells in tumor management. PART 04 The future of reinfusing NK cells: a new direction for personalized immunotherapy

With the development of biotechnology, the treatment of NK cells is moving towards personalization.

We can use gene editing technology to create CAR-NK cells that specifically recognize specific cancers, bringing the precision of immunotherapy to a new level.

In addition, combined with other immune checkpoint inhibitors, such as PD-1 or TIGIT blocking therapy, the efficacy of NK cells has been further amplified.

PART 05 Conclusion: A key step in tumor recovery

In summary, NK cell reinfusing is a promising anti-recurrence and rehabilitation therapy for tumors after surgery.

In the face of the long-term battle against cancer, we not only need to remove the tumor, but also repair the immune system to prevent the enemy from making a comeback. With the development of technology, I believe that NK cells will play a more important role in cancer treatment.